DICETEL® (100 tablets)

DICETEL® contains the active ingredient pinaverium bromide, a quaternary ammonium compound that acts as a calcium channel blocker and antispasmodic agent. It is available in 50mg and 100mg tablets for oral administration.

Indications

DICETEL® is indicated for the treatment of symptoms related to Irritable Bowel Syndrome (IBS), including abdominal pain, diarrhea, constipation, and intestinal discomfort. It helps reduce bowel spasms, contractions, and motility disorders associated with IBS.

Dosage and Administration

The recommended dosage of DICETEL® for adults is 50-100mg twice daily taken 30-60 minutes before meals. The total daily dose should not exceed 300mg. Dosage may be adjusted based on individual response and tolerability. Tablets should be taken with a full glass of water and not crushed or chewed. Treatment with DICETEL® is typically long-term for chronic IBS symptom management.

Contraindications

DICETEL® is contraindicated in patients with:

– Known hypersensitivity to pinaverium bromide or other components of DICETEL®

– Obstructive disease of the GI tract

– Unstable cardiovascular status

– Myasthenia gravis

– Glaucoma

– Obstructive uropathy

Warnings and Precautions

– Use caution when driving or operating machinery as DICETEL® may cause dizziness or drowsiness

– Use with caution in patients with hepatic impairment

– May exacerbate the anticholinergic effects of other drugs with anticholinergic properties

Adverse Reactions

Common adverse reactions include:

– Drowsiness

– Dizziness

– Blurred vision

– Dry mouth

– Nausea

– Vomiting

– Constipation

– Abdominal pain

– Rash

Discontinue DICETEL® if severe reactions occur.

Drug Interactions

DICETEL® should not be used in combination with:

– Antacids – may decrease absorption

– Antidiarrheals – increased risk of constipation

– Cholinergic drugs – decreased efficacy due to opposing effect