CREON® Canadian Formulation (100 capsules)

NOTE TO THE HEALTH PROFESSIONAL AND PURCHASER

CREON® is a difficult product to equivalate between countries as the formulation and the way Units are represented are different.

CREON® 10
Lipase 10,000 Ph. Eur Units =  10,000 USP units
Amylase 8,000 Ph Eur Units= 33,200 USP units
Protease 600 Ph. Eur Units= 37,500 USP units

CREON® 25
Lipase 25,000 Ph. Eur Units= 25,000 USP units
Amylase 25500 Ph. Eur Units= 105,825 USP units
Protease 1600 Ph. Eur Units= 100,000 USP units

CREON® 35
Lipase 35,000 Ph. Eur Units= 25,000 USP units

Pharmacopoeial units other than USP may be represented on the label as additional information.
The following approximate conversion factors can be used to convert the activities of pancreatic enzymes into USP units (Scharpé et al. 1997):
Amylase: 1 Ph. Eur. Unit = 1 BP Unit = 1 FIP Unit ~ 4.15 USP Units